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中药资源方向

冷梁

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基本情况

冷梁,副教授/硕导。方向为本草基因组学,以(共同)一作或通讯在Nature Ecology and Evolution, Nature Communications, Plant Journal, Molecular Ecology, Horticulture Research等国际杂志发表多篇文章。2012年获中国科学院院长优秀奖。研究兴趣为应用新的测序技术手段和分析方法研究结构变异(Structural Variation)和药用植物基因组演化;多组学技术在天然产物和人类基因组GPCR研究中的应用。邮件:llingATcdutcm.edu.cn (发邮件时请将AT换成@)。

近期论文

1,Yujun Zhang#, Qi Shen#, Liang Leng#, Dong Zhang, Sha Chen, Yuhua Shi, Zemin Ning, Shilin Chen. Incipient diploidization of the medicinal plant Perilla within 10,000 years. Nature Communications, 2021, 12(1):5508.

2,Sun W#, Leng L#, Yin Q#, Xu M, Huang M, Xu Z, Zhang Y, Yao H, Wang C, Xiong C, Chen S, Jiang C, Xie N, Zheng X, Wang Y, Song C, Peters RJ, Chen SL. The genome of the medicinal plant Andrographis paniculata provides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide. The Plant Journal, 2019, 97(5):841-57.

3,Fanbo Meng, Tianzhe Chu, Pengmian Feng, Nan Li, Chi Song, Chunjin Li, Liang Leng*, Xiaoming Song*, Wei Chen*. Genome assembly of Polygala tenuifolia provides insights into its karyotype evolution and triterpenoid saponin biosynthesis. Horticulture Research, 2023, 10 (9), uhad139.

4,Zhaoyu Liu, Yupeng Du, Zhihao Sun, Bohan Cheng, Zenghao Bi, Zhicheng Yao, Yuting Liang, Huiling Zhang, Run Yao, Shen Kang, Yuhua Shi, Huihua Wan, Dou Qin, Li Xiang*, Liang Leng*, Shilin Chen*. Manual correction of genome annotation improved alternative splicing identification of Artemisia annua. Planta, 2023, 258 (4), 1-14.

5,Dan Zhang#, Liang Leng#, Chunyan Chen, Jiawei Huang, Yaqiong Zhang, Hao Yuan, Chenyu Ma, Hua Chen, Yong E. Zhang. Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans. Nature Ecology and Evolution, 2022, 6(3):273-287. 

终审:药学院管理员