成谦
一、个人简介
成谦,副研究员,硕士生导师,威尼斯98488引进人才。于四川大学获得化学学士学位,澳门大学获得中药学硕士学位和生物医药博士学位,在化学、纳米材料、和药剂学方面拥有多学科背景和经验。承担国家自然科学基金青年科学基金项目、中国博士后科学基金面上资助项目、四川省天府峨眉计划(原千人计划)青年人才项目等国家级、省部级等项目。研究成果以第一作者身份在Materials Today, Advanced Functional Materials, Theranostics, Materials Horizons, Small等SCI论文10余篇,累计影响因子140余分。
二、研究领域
1. 仿生药物制剂。
2. 新型生物材料。
三、部分代表性成果
1. Qian Cheng, Xingping Quan, Ruifeng Luo, Zhiqing Yang, Junyan Li, Ziyi Wang, Yonghua Zhao, Chunhai Fan, Ruibing Wang*, In Situ Colonization of Trojan-Yeast for Targeted Glucose Starvation and Reconstruction of Tumor Immune Environment, Advanced Functional Materials, 2024, 34, 2316701.
2. Qian Cheng, Zhiqing Yang, Xingping Quan, Yuanfu Ding, Junyan Li, Ziyi Wang, Yonghua Zhao, Xiaoyuan Chen*, Ruibing Wang*, Tumor polyamines as guest cues attract host-functionalized liposomes for targeting and hunting via a bio-orthogonal supramolecular strategy, Theranostics, 2023, 13, 611.
3. Qian Cheng, Meng Xu, Chen Sun, Kuikun Yang, Zhiqing Yang, Junyan Li, Jun Zheng, Ying Zheng and Ruibing Wang*, Enhanced antibacterial function of a supramolecular artificial receptor-modified macrophage (SAR-Macrophage), Materials Horizons, 2022, 9, 934.
4. Qian Cheng, Ludan Yue, Junyan Li, Cheng Gao, Yuanfu Ding, Chen Sun, Mengze Xu, Zhen Yuan, Ruibing Wang*, Supramolecular Tropism Driven Aggregation of Nanoparticles In Situ for Tumor Specific Bioimaging and Photothermal Therapy, Small, 2021, 17, 2101332.
5. Hang Yin, Qian Cheng (co-first author), David Bardelang,* Ruibing Wang*, “Challenges and opportunities of functionalized cucurbiturils for biomedical applications,” JACS Au, 2023, DOI:10.1021/jacsau.3c00273.
6. Cheng Gao, Qian Cheng (co-first author), Junyan Li, Jia Chen, Qingfu Wang, Jianwen Wei, Qiaoxian Huang, Simon M. Y. Lee*, Dayong Gu*, Ruibing Wang*, Supramolecular macrophage liposome marriage for cell hitchhiking delivery and immunotherapy of acute pneumonia and melanoma. Advanced Functional Materials, 2021, 31, 2102440.
7. Junyan Li, Qian Cheng (co-first author), Ludan Yue, Cheng Gao, Jianwen Wei, Yuanfu Ding, Yitao Wang, Ying Zheng and Ruibing Wang*, Macrophage-hitchhiking supramolecular aggregates of CuS nanoparticles for enhanced tumor deposition and photothermal therapy, Nanoscale Horizons, 2021, 6, 907.
8. Cheng Gao, Qian Cheng (co-first author), Jianwen Wei, Chen Sun, Siyu Lu, Cheryl H. T. Kwong, Simon M. Y. Lee, Zhiyuan Zhong*, Ruibing Wang*, Bioorthogonal supramolecular cell-conjugation for targeted hitchhiking drug delivery. Materials Today, 2020, 40, 9.
9. Qian Cheng, Shengke Li, Yanlong Ma, Hang Yin and Ruibing Wang*, pH-Responsive supramolecular DOX-dimer based on cucurbit[8]uril for selective drug release. Chinese Chemical Letters, 2020, 31, 1235.
10. Qian Cheng, Kun-Xu Teng, Yuan-Fu Ding, Ludan Yue, Qing-Zheng Yang* and Ruibing Wang*, Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells, Chemical Communications, 2019, 55, 2340.
11. Qian Cheng, Shengke Li, Chen Sun, Ludan Yue and Ruibing Wang*, Stimuli-responsive perallyloxycucurbit[6]uril-based nanoparticles for selective drug delivery in melanoma cells. Materials Chemistry Frontiers, 2019, 3, 199.