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中药制剂与炮制方向

彭伟

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一、个人简介    

   彭伟,博士、博士后、副教授、硕士生导师,现工作于威尼斯98488药学院。世界中医药学会联合会翻译专业委员会常务理事、中国民族医药学会方药量效研究分会常务理事、世界中医药学会联合会中药调剂委员会理事、中国中医药信息会李时珍研究分会理事。TMR Integrative Medicine主编、Frontiers in Pharmacology 副主编(Ethnopharmacology section)、中医杂志(英文版)Letter to the editor专栏编辑和青年编委、中草药(英文版)青年编委、Current Medicine编委、Acta Materia Medica青年编委、西南医科大学学报青年编委;Medicinal Research ReviewsPharmacological ResearchPhytomedicine 等杂志审稿人。

主要研究方向为中药炮制与制剂、中药及复方药效物质基础。主持中国博士后基金一等资助、四川省自然科学基金等部省级课题3项、厅局级课题3项、主研国家级/省部级课题8项。H-index 33Web of Science),发表学术论文100余篇,以第一或通讯作者在Pharmacological ResearchJournal of Advanced ResearchPhytomedicineSCI杂志发表论文70余篇,被Nature Metabolism等杂志正面引用3000余次,单篇最高被引207次,ESI高被引论文9篇。获得授权发明专利3项,适用新型专利2项,软件著作权1项。

联系方式:成都市温江区柳台大道1166号威尼斯98488药学院东耳房

Email: pengwei@cdutcm.edu.cn

二、代表性成果

(1) Qing Zhang, Chengxun He, Lingyu Wang, Die Qian, Dandan Tang, Shengnan Jiang, Wenwen Chen, Chunjie Wu*, Wei Peng*. Hydroxy-α-sanshool from the fruits of Zanthoxylum bungeanum Maxim. promotes browning of white fat by activating TRPV1 to induce PPAR-γ deacetylation. Phytomedicine, 2023, 121: 155113.

(2) Wei Peng#, Chengxun He#, Ruolan Li, Die Qian, Lingyu Wang, Wenwen Chen, Qing Zhang*, Chunjie Wu*. Zanthoxylum bungeanum amides ameliorates nonalcoholic fatty liver via regulating gut microbiota and activating AMPK/Nrf2 signaling. Journal of Ethnopharmacology, 2024, 318: 116848.

(3) Chengxun He, Ke Wang, Jun Xia, Die Qian, Juan Guo, Lian Zhong, Dandan Tang, Xiuping Chen, Wei Peng*, Yunhui Chen* and Yong Tang*. Natural exosomes-like nanoparticles in mung bean sprouts possesses anti-diabetic effects via activation of PI3K/Akt/GLUT4/GSK-3β signaling pathway. Journal of Nanobiotechnology, 2023, 21:349.

(4) Bingke Bai, Chang Liu, Chengzhong Zhang, Xuhui He, Hongrui Wang, Wei Peng*, Chengjian Zheng*. Trichoderma species from plant and soil: An excellent resource for biosynthesis of terpenoids with versatile bioactivities. Journal of Advanced Research, 2023, 49: 81-102.

(5) Qi Liang, Jingwen Wang, Yuru Bai, Ruolan Li, Chunjie Wu*, Wei Peng*. Targeting TRPV1 and TRPA1: A feasible strategy for natural herbal medicines to combat postoperative ileus. Pharmacological Research, 2023, 196: 106923.

(6) Qing Zhang, Die Qian, Dandan Tang, Jia Liu, Linyu Wang, Wenwen Chen, Chunjie Wu*, Wei Peng*. Glabridin from Glycyrrhiza glabra possesses a therapeutic role against keloid via attenuating PI3K/Akt and transforming growth factor-β1/SMAD signaling pathways. Journal of Agricultural and Food Chemistry, 2022,70(35):10782-10793.

(7) Mengmeng Zhang, Daneng Wei, Lin He, Dan Wang, Li Wang, Dandan Tang, Rong Zhao, Xun Ye, Chunjie Wu*, Wei Peng*. Application of response surface methodology (RSM) for optimization of the supercritical CO2 extract of oil from Zanthoxylum bungeanum pericarp: Yield, composition and gastric protective effect. Food Chemistry:X, 2022, 15, 100391.

(8) Qing Zhang, Wenwen Chen, Xue Sun, Die Qian, Dandan Tang, Lilin Zhang, Meiyan Li, Linyu Wang, Chunjie Wu*, Wei Peng*. The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers. International Journal of Biological Sciences, 2022, 18(8): 3498-3527.

(9) Wei Peng#, Yunhui Chen#,*, Steve Tumilty, Lizhou Liu, Ling Luo, Haiyan Yin, Yongmei Xie. Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis. Current Opinion in Pharmacology, 2022, 62:97-102.

(10) Qing Zhang, Jia Liu, Xinyue Duanhu, Ruolan Li, Wei Peng, Chunjie Wu. Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress. Journal of Advanced Research,2021,34:43-63

(11) Huxinyue Duan#, Qing Zhang#, Jia Liu, Ruolan Li, Dan Wang, Wei Peng*, Chunjie Wu*. Suppression of apoptosis in vascular endothelial cell, the promising way for natural medicines to treat atherosclerosis. Pharmacological Research 2021, 168: 105599

(12) Yu Long, Qiyue Yang, Yan Xiang, Yulu Zhang, Jinyan Wan, Songyu Liu, Nan Li*, Wei Peng*. Nose to brain drug delivery - a promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion. Pharmacological Research 2020, 159: 104795

(13) Yulu Zhang, Yu Long, Shuang Yu, Dan Li, Ming Yang, Yongmei Guan, Dingkun Zhang, Jinyan Wan, Songyu Liu, Ai Shi, Nan Li*, Wei Peng*. Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder. Pharmacological Research 2021, 164: 105376.

(14) Qing Zhang#, Wei Peng#, Shujun Wei, Daneng Wei, Ruolan Li, Jia Liu, Lanyu Peng, Shuang Yang, Yongxiang Gao*, Chunjie Wu*, Xufeng Pu*. Guizhi-Shaoyao-Zhimu decoction possesses anti-arthritic effects on type II collagen-induced arthritis in rats via suppression of inflammatory reactions, inhibition of invasion & migration and induction of apoptosis in synovial fibroblasts. Biomedicine & Pharmacotherapy 2019, 118: 109367.

(15) Mengmeng Zhang#, Mingguo Xie#, Daneng Wei, Li Wang, Meibian Hu, Qing Zhang, Zuxing He, Wei Peng*, Chunjie Wu*. Hydroxy-α-sanshool isolated from Zanthoxylum bungeanum attenuates learning and memory impairments in scopolamine-treated mice. Food & Function 2019, 10:7315-7324. 

终审:药学院管理员