一、个人简介

  张杨，威尼斯98488中医药创新研究院副教授，长期致力于生物信息学领域的研究工作，目前已成功开发了多个生物医学相关数据库、算法和分析平台，为来自30多个国家和地区的科研人员提供了重要的服务和资源支持，其中部分工作对单细胞组学及RNA组学研究领域具有重要推动作用，主要研究成果以第一作者或通讯作者的身份发表在《Nucleic Acids Research》、《Briefings in Bioinformatics》、《Bioinformatics》等生物信息学领域的顶级刊物上（IF高于15的论文2篇、IF高于10的论文4篇），目前已主持多项国家级和省部级科学基金项目（主持国家自然科学基金1项、省部级自然科学基金2项、生物制药企业横向基金1项）。邮箱：yangzhang@cdutcm.edu.cn。实验室网站：http://www.zhangy-lab.cn/。

二、主要研究方向

（1） 中医药相关数据资源整合及数据库开发；

（2） AI辅助的药物设计研究；

（3） 单细胞测序数据挖掘及算法开发。

三、近三年科研成果

已发表或接受的第一作者及通讯作者论文：

2023年：

[1] Yang Zhang, Caiqi Liu, Mujiexin Liu, Tianyuan Liu, Hao Lin, Chengbing Huang, Lin Ning. Attention is all you need: Utilizing attention in AI-enabled drug discovery. Briefings in Bioinformatics, 2023.（accepted）（2023 IF: 9.5）.

[2] Yang Zhang, Xianrun Pan, Tianyu Shi, Zhifeng Gu, Zhaochang Yang, Minghao Liu, Yi Xu, Yu Yang, Liping Ren, Xiaoming Song, Hao Lin, Kejun Deng. P450Rdb: a manually curated database of reactions catalyzed by cytochrome P450 enzymes. Journal of Advanced Research. （2023 IF: 10.7）.

[3] Liping Ren, Lin Ning, Yu Yang, Ting Yang, Xinyu Li, Shanshan Tan, Peixin Ge, Shun Li, Nanchao Luo, Pei Tao, Yang Zhang. MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19. Computers in Biology and Medicine, 167, 107661. （2023 IF: 7.7）.

[4] Yu-Fei Zhang, Yu-Hao Wang, Zhi-Feng Gu, Xian-Run Pan, Jian Li, Hui Ding, Yang Zhang, Ke-Jun Deng. Bitter-RF: a random forest machine model for recognizing bitter peptides. Frontiers in Medicine,2023,10, 1052923. （2023 IF: 3.9，全球高被引论文）.

2022年：

[5] Hao Lv, Yang Zhang, Jia-Shu Wang, Shi-Shi Yuan, Zi-Jie Sun, Fu-Ying Dao, Zheng-Xing Guan, Hao Lin*, Ke-Jun Deng*, iRice-MS: An integrated XGBoost model for detecting multitype post-translational modification sites in rice, Briefings in Bioinformatics, 2022, 23(1): bbab486. （2022 IF: 11.622）.

[6] Liping Ren, Yi Xu, Lin Ning, Xianrun Pan, Yuchen Li, Qi Zhao, Bo Pang, Jian Huang*, Kejun Deng*, Yang Zhang. TCM2COVID: A resource of anti‐COVID‐19 traditional Chinese medicine with effects and mechanisms. iMeta, 2022, 1(4): e42（国产期刊）.

[7] 任丽萍, 宁琳, 谢雷, 张杨. 肿瘤免疫微环境中免疫细胞间通讯景观探究.电子科技大学学报, 2022,51(2):177-183. （EI）.

2021年：

[8] Yang Zhang, Tianyuan Liu, Xuesong Hu, Mei Wang, Jing Wang, Bohao Zou, Puwen Tan, Tianyu Cui, Yiying Dou, Lin Nin, Yan huang, Shuan Rao, Dong Wang, Xiaoyang Zhao. CellCall: Integrating paired ligand-receptor and transcription factor activities for cell-cell communication. Nucleic Acids Research, 2021, 49(15): 8520-8534. （2021 IF: 19.16）.

[9] Yan Huang, Jing Wang, Yue Zhao, Huafeng Wang, Tianyuan Liu, Yuhe Li, Tianyu Cui, Weiyi Li, Yige Feng, Jiaxin Luo, Jiaqi Gong, Lin Ning, Yong Zhang*, Dong Wang*, Yang Zhang. cncRNAdb: a manually curated resource of experimentally supported RNAs with both protein-coding and noncoding function. Nucleic Acids Research, 2021, 49(D1): D65-D70. （2021 IF: 19.16）.

[10] Yang Zhang, Tianyuan Liu, Jing Wang, Bohao Zou, Le Li, Linhui Yao, Kechen Chen, Lin Ning, Bingyi Wu, Xiaoyang Zhao, Dong Wang. Cellinker: a platform of ligand-receptor interactions for intercellular communication analysis. Bioinformatics. 2021. 37(14): 2025-2032. （2021 IF: 6.931）.

[11] Hao Lv, Lei Shi, Joshua William Berkenpas, Fu-Ying Dao, Hasan Zulfiqar, Hui Ding, Yang Zhang, Liming Yang, Renzhi Cao. Application of artificial intelligence and machine learning technologies for SARS-CoV-2 drugs and vaccines. Briefings in Bioinformatics, 2021, 22(16): bbab320. （2021 IF: 13.994）.