一、个人简介

冯五文，中药药理学博士，副教授，硕士生导师，全国中医药优秀博士学位论文获得者，省部共建西南特色中药资源国家重点实验室固定人员。主持国家自然科学基金青年项目、中国博士后基金面上项目、四川省科技厅项目、威尼斯98488杏林学者潜质博士后项目等多项。以第一作者或通讯作者身份在Theranostics，Science of the Total Environment，Analytica Chimica Acta，Pharmacological Research，Food Research International等国际知名期刊发表SCI 论文近30篇，单篇最高影响因子11.556，入选ESI高被引论文4篇，H指数20，入选2022、2023年度全球前2%顶尖科学家影响力榜单。担任《中草药》青年编委、Frontiers in Pharmacology编委，Trends in Food Science & Technology、Advanced Drug Delivery Reviews、Phytomedicine等10余期刊审稿人。

联系方式：jiaoxiake-1@foxmail.com; 304490947@qq.com

二、研究方向

1. 中药与肠道菌群的相互作用研究，如人参、白术、附子、参术膏等对肠道菌群的调控作用。

2. 中医证候机理及中药药性研究，如类风湿性关节炎寒证、脾虚湿困型溃疡性结肠炎等的形成机理研究以及附子寒热药性的研究。

三、代表性论文

[1] Juan Liu, Fu Peng, Hao Cheng, Dandan Zhang, Yuxi Zhang, Lixia Wang, Fei Tang, Jing Wang, Yan Wan, Jing Wu, Yinlin Zhou, Wuwen Feng*, Cheng Peng*. Chronic cold environment regulates rheumatoid arthritis through modulation of gut microbiota-derived bile acids. Science of The Total Environment 2023; 903(10): 166837.（中科院一区）

[2] Wuwen Feng, Juan Liu, Hui Ao, Shijun Yue, Cheng Peng*. Targeting gut microbiota for precision medicine: Focusing on the efficacy and toxicity of drugs. Theranostics 2020; 10(24): 11278-11301. (中科院一区)

[3] Hao Cheng^#, Juan Liu^#, Dandan Zhang, Jing Wang, Yuzhu Tan, Wuwen Feng*, Cheng Peng*. Ginsenoside Rg1 alleviates acute ulcerative colitis by modulating gut microbiota and microbial tryptophan metabolism. Frontiers in Immunology 2022; 13: 817600. (中科院二区)

[4] Juan Liu^#, Yuzhu Tan^#, Hao Cheng, Dandan Zhang, Wuwen Feng*, Cheng Peng*. Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives. Aging and Disease 2022; 13(4): 1106-1126.（中科院一区，高被引论文）

[5] Hao Cheng^#, Juan Liu^#, Yuzhu Tan, Wuwen Feng*, Cheng Peng*. Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine. Journal of Pharmaceutical Analysis 2022; 12(4): 541-555.（中科院一区，高被引论文）

[6] Wuwen Feng, Juan Liu, Yuzhu Tan, Hui Ao, Jing Wang, and Cheng Peng*. Polysaccharides from Atractylodes macrocephala Koidz. Ameliorate ulcerative colitis via extensive modification of gut microbiota and host metabolism. Food Research International 2020; 138: 109777. （中科院一区)

[7] Juan Liu, Yuzhu Tan, Hui Ao, Wuwen Feng*, and Cheng Peng*. Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism. Chinese medicine 2021; 16(1): 29. (中科院三区)

[8] Wuwen Feng, Hui Ao, Cheng Peng*. Gut microbiota, short-chain fatty acids, and herbal medicines. Frontiers in Pharmacology 2018; 9: 1354. (中科院二区，高被引论文）

[9] Wuwen Feng, Hui Ao, Cheng Peng*, Dan Yan. Gut microbiota, a new frontier to understand traditional Chinese medicines. Pharmacological Research 2019; 142: 176-191. (中科院二区，高被引论文）

[10] Dandan Zhang^#, Juan Liu^#, Hao Cheng, Hongliang Wang, Yuzhu Tan, Wuwen Feng*, Cheng Peng*. Interactions between polysaccharides and gut microbiota: A metabolomic and microbial review. Food Research International. 2022; 160: 111653. （中科院一区）