【导师】康娟娟,特聘副研究员,硕士生导师。2020年于电子科技大学获生物医学工程博士学位,同年加入南方医科大学从事博士后研究,2022年博士后出站。长期从事生物医药大数据和人工智能的生物信息学研究。现任中国自动化学会智能健康与生物信息专委会委员,四川省生物信息学会智慧免疫分会委员,四川省生物信息学会青年委员会委员。主持国家自然科学基金青年基金、广东省基础与应用基础研究基金区域联合基金,获中国博士后科学基因面上资助。目前以第一作者或通讯作者在Signal Transduction and Targeted Therapy、Nucleic Acids Research、Bioinformatics等国际知名期刊发表SCI论文十余篇,累计影响因子大于90,总引用超200次。邮箱:kangjuanjuan@cdutcm.edu.cn。
主要研究方向:基于人工智能的药用植物天然产物的活性研究;药用植物天然产物的数据平台构建
代表性成果:
1.Juanjuan Kang, Sisi Yu, Song Lu, Guohui Xu, Jiang Zhu, Na Yan, Delun Luo, Kai Xu, Zhihui Zhang, Jian Huang. Use of a 6-miRNA panel to distinguish lymphoma from reactive lymphoid hyperplasia. Signal Transduct Target Ther. 2020;5(1):2. (Top期刊, IF=39.3)
2.Juanjuan Kang, Qiang Tang, Jun He, Le Li, Nianling Yang, Shuiyan Yu, Mengyao Wang, Yuchen Zhang, Jiahao Lin, Tianyu Cui, Yongfei Hu, Puwen Tan, Jun Cheng, Hailong Zheng, Dong Wang, Xi Su, Wei Chen, Yan Huang. RNAInter v4.0: RNA interactome repository with redefined confidence scoring system and improved accessibility. Nucleic Acids Res. 2022;50(D1):D326-D332. (Top期刊, IF=14.9, Cited=67)
3.Deng Wu*, Yan Huang*, Juanjuan Kang*, Kongning Li, Xiaoman Bi, Ting Zhang, Nana Jin, Yongfei Hu, Puwen Tan, Lu Zhang, Ying Yi, Wenjun Shen, Jian Huang, Xiaobo Li, Xia Li, Jianzhen Xu, Dong Wang. ncRDeathDB: A comprehensive bioinformatics resource for deciphering network organization of the ncRNA-mediated cell death system. Autophagy. 2015;11(10):1917-1926. (并列一作, Top期刊, IF=13.3, Cited=57)
4.Ruixuan Chen, Ping Ouyang, Licong Su, Xi Xu, Penghu Lian, Yanqin Li, Qi Gao, Yifan Zhang, Sheng Nie, Fan Luo, Ruqi Xu, Xiaodong Zhang, Xiaoxi Li, Yue Cao, Peiyan Gao, Juanjuan Kang#, Jun Wu#, Lu Li#. Nanoparticles targeting at methylases with high correlation to N-6-methyladenosine-related lncRNA signatures as potential therapy of kidney clear cell carcinoma. Chinese Chem Lett. 2022;33(10):4610-4616. (并列通讯, Top期刊, IF=8.455, Cited=10)
5.Qiang Tang*, Juanjuan Kang*, Jiaqing Yuan, Hua Tang, Xianhai Li, Hao Lin, Jian Huang, Wei Chen. DNA4mC-LIP: a linear integration method to identify N4-methylcytosine site in multiple species. Bioinformatics. 2020;36(11):3327-3335. (并列一作, IF= 5.8, Cited=31)
6.Juanjuan Kang, Yewei Fang, Pengcheng Yao, Ning Li, Qiang Tang, Jian Huang. NeuroPP: A Tool for the Prediction of Neuropeptide Precursors Based on Optimal Sequence Composition. Interdiscip Sci. 2019;11(1):108-14. (IF= 4.8,Cited=34)
7.Juanjuan Kang, Pengcheng Yao, Qiang Tang, Ying Wang, Yuwei Zhou, Jian Huang. Systematic Analysis of Competing Endogenous RNA Networks in Diffuse Large B-Cell Lymphoma and Hodgkin's Lymphoma. Front Genet. 2020;11:586688.
8.Juanjuan Kang, Guishu Yang, Dongsheng Wang, Ying Lin, Qifeng Wang, Huaichao Luo. The Clinical Application Value of the Prognostic Nutritional Index for the Overall Survival Prognosis of Patients with Esophageal Cancer: A Robust Real-World Observational Study in China. Comput Math Methods Med. 2022;2022:3889588.
9.Ying Wang*, Juanjuan Kang*, Ning Li, Yuwei Zhou, Zhongjie Tang, Bifang He, Jian Huang. NeuroCS: A Tool to Predict Cleavage Sites of Neuropeptide Precursors. Protein Pept Lett. 2020;27(4):337-345. (并列一作)
10.Yongfei Hu, Yinglun Luo, Guangjue Tang, Yan Huang#, Juanjuan Kang#, Dong Wang#. Artificial intelligence and its applications in digital hematopathology. Blood Sci. 2022;4(3):136-142. (并列通讯)
科研项目:
1.深度学习视域下双功能lncRNA的识别及其在DLBCL中多维互作调控网络的系统研究,62302066,国家自然科学基金青年基金,2024/01-2026/12,主持
2.基于深度学习的人类双功能长非编码 RNA识别算法研究,2021A1515110653,广东省基础与应用基础研究基金区域联合基金,2021/10-2024/09,主持
3.基于单细胞测序技术解析小鼠成体造血干细胞分化过程中RNA结合蛋白的功能及其调控机制,2020M682785,中国博士后科学基金面上资助,2021/01-2022/07,主持
4.转录组分子标记时相变化规律与组织离体时间推断研究,82293652,国家自然科学基金重大项目,2023/01-2027/12,参与
5.基于深度学习的阻断NMDAR/TRPM4相互作用的多肽设计系统研究,62261006,国家自然科学基金地区科学基金项目,2023/01-2026/12,参与
6.结核杆菌细胞被膜完整结构粗粒度模型的构建及其抗药机理研究,31971176,国家自然科学基金面上项目,2020/01-2023/12,参与